Recombinant TBEV PreM Protein |
Tick-borne encephalitis virus (TBEV) is the virus associated with tick-borne encephalitis, a virus infectious disease affecting humans in Europe and Asia. TBEV is a member of the genus Flavivirus. TBEV has three subtypes: Western European subtype (formerly Central European encephalitis virus, CEEV; principal tick vector: Ixodes ricinus); Siberian subtype (formerly West Siberian virus; principal tick vector: Ixodes persulcatus); Far Eastern subtype (formerly Russian Spring Summer encephalitis virus, RSSEV; principal tick vector: Ixodes persulcatus). TBEV now is known to infect multiple hosts including ruminants, carnivores, birds, rodents, horses and humans, and the TBE disease can be zoonotic too. TBE often manifests as encephalitis, meningitis, or meningoencephalitis.