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Keyword "CASP3"
Caspase 3 Human, Recombinant Caspase 3 Human, Recombinant

Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase 3 is considered to be an effector caspase, activating pro-caspase 6 and pro-caspase 9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B.


[Related Categories: Bio-technology Products ]
[Related Keywords: CASP3, Recombinant (Human) ]